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The process of physiological respiration includes two major parts: external respiration and internal respiration. External respiration, also known as breathing, involves both bringing air into the lungs (inhalation) and releasing air into the atmosphere (exhalation). During internal respiration, oxygen and carbon dioxide are exchanged between the cells and blood vessels.

Respiration begins at the nose or mouth, where oxygenated air is brought in before moving down the pharynx, larynx, and the trachea. The trachea branches into two bronchi, each leading into a lung. Each bronchus divides into smaller bronchi, and again into even smaller tubes called bronchioles. At the end of the bronchioles are air sacs called alveoli, and this is where gas exchange occurs.